Emmanuel Cascione
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| Position | Midfielder |
| Height / weight | 1.87 m / 77 kg |
| Born | 22 Sept 1983 (42 years) |
| Nationality |  Italy |
| Number | 34 |
Emmanuel Cascione is an Italian football player who currently features for the Italian football club Reggina. He plays as a midfielder.
Emmnauel Cascione commenced his professional club football career at Pistoiese in 2000 and played for them until 2005, scoring 5 goals in 76 international matches.
He then moved to Rimini in 2005 and played for them for two seasons, scoring four goals in 56 league appearances.
In 2007 Emmanuel Cascione was signed by Reggina.