The Norwegian forward was replaced at the break having copped a knock, although City boss Pep Guardiola seemed cautiously optimistic about his availability.
“Erling has a kick and we will see,” Guardiola told reporters. “We will assess him in the next few days to see how severe it is.
“At half-time I spoke with the doctors to see and they said maybe at 3-0 we don’t need to take a risk and I agreed with the doctors.
“If the score was more tight maybe I wouldn’t do it. I think he’s not injured but tomorrow we will see.
“Hopefully he can play there on Wednesday. If he’s not ready or it’s a risk he’s not going to play.”
The result sees City move within three points of leaders Arsenal who were held to a 1-1 home draw with Brentford on Saturday.
City have played one more game than Arsenal, but the Gunners have dropped points in three of their past five league games.
“Today I had the feeling that every game will be so difficult,” Guardiola added.
“The players at the bottom of the league are fighting for so many things. Every game is tougher and tougher.
“We will travel to London to play our game. Especially the way we are behaving in the training sessions in the last week to 10 days, we improved a lot.
“Everyone is so focused, not just the performances. You have to have the chance to be competitive - that doesnt ensure you will win, but without that it is impossible.”