The Hammers played out a 1-1 draw with United away from home at Old Trafford in the Premier League.
Antonio put West Ham in the lead in the second minute of first-half injury time when he found the net from the penalty spot.
Mason Greenwood restored parity for the Red Devils six minutes into the second half, as the match ended in a 1-1 draw.
Antonio has taken to Twitter to revel in scoring yet another goal for West Ham, and believes that there is more to come from him.
Buzzing to be having my best goal scoring Prem season and we aint done yet. Lets finish on a high this weekend #COYI pic.twitter.com/6xYPtRuzqv
— Michail Antonio (@Michailantonio) July 22, 2020
Stats
Antonio has made 18 starts and five substitute appearances in the Premier League for West Ham this season, scoring 10 goals and providing three assists in the process.
During the 2018-19 campaign, the former Sheffield Wednesday and Nottingham Forest winger made 22 starts and 11 substitute appearances in the league for the Hammers, scoring six goals and providing four assists in the process.
West Ham are 15th in the Premier League table at the moment with 38 points from 37 matches, four points above the relegation zone, and will not go down to the Championship.