The Argentina international, who can operate as a forward or as an attacking midfielder, has been suffering from the disease for over a month.
Dybala and girlfriend, Oriana Sabatini, announced that they had contracted the virus back on March 21.
The 26-year-old has now started on Twitter that he has completely recovered from the virus, with his club Juventus saying that the Argentine star will no longer be subjected to the home isolation regime.
Many people talked in the past weeks ... but I can finally confirm that I am healed. Thank you once again for your support and my thoughts on all who are still suffering from it. Take care! ️
— Paulo Dybala (@PauDybala_JR) May 6, 2020
Football in Italy is suspended at the moment due to the coronavirus pandemic, and it remains to be seen when the season resumes.
Juventus are at the top of the Serie A table at the moment with 63 points from 26 matches, a point clear of second-placed Lazio.
Dybala has made 17 starts and seven substitute appearances in Serie A for the Bianconeri so far this campaign, scoring seven goals and providing four assists in the process.
The attacker has also made three starts and four substitute appearances in the Champions league for Juventus this season, scoring three goals and providing two assists in the process.